OPEN PARTIAL HORIZONTAL LARYNGECTOMY AS A CONSERVATIVE SALVAGE TREATMENT FOR LASER-RECURRENT LARYNGEAL CANCER: A MULTI-INSTITUTIONAL SERIES

Open Partial Horizontal Laryngectomy as a Conservative Salvage Treatment for Laser-Recurrent Laryngeal Cancer: A Multi-Institutional Series

Early-stage laryngeal cancer (T1-T2) is commonly treated with organ-preserving techniques such as transoral laser microsurgery (TOLMS) or radiation therapy (RT), both providing comparable oncological outcomes but differing in functional results.Local recurrence occurs in approximately 10% of cases, making salvage surgery a crucial therapeutic optio

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K+ channels and cell cycle progression in tumor cells

K+ ions play a major role in many cellular Hoover HBD 495D2E Integrated Washer Dryer 9/5kg - White 9kg washing capacity processes.The deregulation of K+ signaling is associated with a variety of diseases such as hypertension, atherosclerosis, or diabetes.K+ ions are important for setting the membrane potential, the driving force for Ca2+ influx, an

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Disturbed intracellular folate homeostasis impairs autophagic flux and increases hepatocytic lipid accumulation

Abstract Background Metabolic associated fatty liver disease (MAFLD), a prevalent liver disorder affecting one-third of the global population, encompasses a spectrum ranging from fatty liver to severe hepatic steatosis.Both genetic and lifestyle factors, particularly diet and nutrition, contribute to its etiology.Folate deficiency, a frequently enc

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